2016年以降（原著論文）

Morita N, Yamamoto K, Tamano R, Gao P, Nagatake T, Inomata T, Huang T, Yamada Y, Adachi T, Sugai M, Nakayama KI, Kojima H, Shinkura R. Regulation of selective class switching provides long-term therapeutic benefits for hay fever. JCI Insight. 2025 Oct 21;10(23):e190240. doi: 10.1172/jci.insight.190240.

Liu Y, Sawada K, Adachi T, Kino Y, Yin T, Yamamoto N, Yamada T. Comparative genome analysis of the immunomodulatory ability of Lactiplantibacillus plantarum and Lactiplantibacillus pentosus from Japanese pickles. mSystems. 2025 10(5):e0157524. doi: 10.1128/msystems.01575-24. Online ahead of print.

Kusumoto Y, Ueda M, Hashimoto M, Takeuchi H, Okada N, Yamamoto J, Nishii A, Fujino A, Kurahashi A, Satoh M, Iwasa Y, Okamura K, Obazaki K, Kumagai R, Sakamoto N, Tanaka Y, Kamiya Y, Hoshida T, Kaisho T, Hemmi H, Katakai T, Honda T, Kikuta J, Kataoka K, Ikebuchi R, Moriya T, Adachi T, Watanabe T, Ishii M, Miyawaki A, Kabashima K, Chtanova T, Tomura M. Sublingual immune cell clusters and dendritic cell distribution in the oral cavity. JCI Insight. 2024 Oct 1;9(21):e167373. doi: 10.1172/jci.insight.167373.

Yuying Bai, Mengying Lyu, Takashi Satoh, Kanami Orihara, Kazuhiko Miyanaga, Takahiro Adachi, Naoyuki Yamamoto. Lactobacillus johnsonii colonizing in mice intestine contributes to control the gut barrier function via regeneration of the crypt in DSS‐treated mice, JSFA Reports, 2024. http://doi.org/10.1002/jsf2.217

Karimazawa M, Adachi T, Sillapakong P, Yamashita, T. Immunostimulatory and Anti-Aging Effects of Sericin Powders Extracted from Antheraea yamamai. Journal of Insect Biotechnology and Sericology 2023 92, 55-64.

Kawamoto S, Uemura K, Hori N, Takayasu L, Konishi Y, Katoh K, Matsumoto T, Suzuki M, Sakai Y, Matsudaira T, Adachi T, Ohtani N, Standley DM, Suda W, Fukuda S, Hara E. Bacterial induction of B cell senescence promotes age-related changes in the gut microbiota. Nat Cell Biol. 2023 May 11. doi: 10.1038/s41556-023-01145-5. (IF=28.213)

Takeuchi, Y., Fukunaga, M., Iwatani, S., Miyanaga, K., Adachi, T., Yamamoto, N. Release of an anti-anxiety peptide in casein hydrolysate with Aspergillus oryzae protease. Food Funct. 2022 Oct 17;13(20):10449-10460. doi: 10.1039/d2fo01793h.

(IF=5.396)

Kotake, K., Kumazawa, T, Adachi, T. Long-term administration of Tetragenococcus halophilus No. 1 over generations affects the immune system of mice. PLoS One, 17(4):e0267473. 2022. (IF=3.240)

Published: April 26, 2022 https://doi.org/10.1371/journal.pone.0267473

Hirata Y, Nomura K, Kato D, Tachibana Y, Niikura T, Uchiyama K, Hosooka T, Fukui T, Oe K, Kuroda R, Hara Y, Adachi , Shibasaki K, Wake H, and Ogawa W. A Piezo1/KLF15/IL-6 axis mediates immobilization-induced muscle atrophy. J Clin Invest. https://doi.org/10.1172/JCI154611.(IF=19.456)

Gao P, Adachi T, Okai S, Morita N, Kitamura D, Shinkura R. Integrin CD11b provides a new marker of pre-germinal center IgA + B cells in murine Peyer's patches. Int Immunol. 2021 Dec 31:dxab113.

doi: 10.1093/intimm/dxab113. Online ahead of print.PMID: 34971392 (IF=4.823)

Kotake, K., Kumazawa, T, Nakamura, K, Shimizu, Y, Ayabe , T., Adachi, T. Ingestion of miso regulates immunological robustness in mice. PLoS One, 17(1):e0261680. 2022. (IF=3.240)

Nagaishi, T., Watabe, T., Kotake, K., Kumazawa, T., Aida, T., Tanaka, K., Ono, R., Ishino, F., Usami, T., Miura, T., Hirakata, S., Kawasaki, H., Tsugawa, N., Yamada, D., Hirayama, K., Yoshikawa, S., Karasuyama, H., Okamoto, R., Watanabe, M., *Blumberg, R.S., and *Adachi, T., Immunoglobulin A-specific deficiency induces spontaneous inflammation specifically in the ileum. Gut. 71(3):487-496. 2022. (IF=24.5)

Tsugawa, N., Yamada, D., Watabe, T., Onizawa, M., Wang, S., Nemoto, Y., Oshima, S., Tsubata, T., Adachi, T., Kawano, Y., Watanabe, M., Blumberg, R.S., Okamoto, R., and *Nagaishi, T., CEACAM1 specifically suppresses B cell receptor signaling-mediated activation. Biochem Biophys Res Commun, 535: 99-105. 2021. (IF=3.575)

Yokoi, Y., Adachi, T., Sugimoto, R., Kikuchi, M., Ayabe, T., and *Nakamura, K., Simultaneous real-time analysis of Paneth cell and intestinal stem cell response to interferon-gamma by a novel stem cell niche tracking method. Biochem Biophys Res Commun, 545: 14-9. 2021. (IF=3.575)

Endo, R., Uchiyama, K., Lim, S.Y., Itakura, M., Adachi, T., and *Uchida, K., Recognition of acrolein-specific epitopes by B cell receptors triggers an innate immune response. J Biol Chem: 100648. 2021. (IF=4.238)

Yasuda, K., *Nakashima, A., Murata, A., Suzuki, K., and *Adachi, T., Euglena Gracilis and beta-Glucan Paramylon Induce Ca(2+) Signaling in Intestinal Tract Epithelial, Immune, and Neural Cells. Nutrients, 12. 2020. (IF=6.706)

Nishimura, Y., Fukuda, Y., Okonogi, T., Yoshikawa, S., Karasuyama, H., Osakabe, N., Ikegaya, Y., *Sasaki, T., and *Adachi, T., Dual real-time in vivo monitoring system of the brain-gut axis. Biochem Biophys Res Commun, 524: 340-5. 2020. (IF=3.575)

Kumazawa, T., Kotake, K., Nishimura, A., Asai, N., Ugajin, T., Yokozeki, H., and *Adachi, T., Isolation of food-derived bacteria inducing interleukin-22 in B cells. Biosci Microbiota Food Health, 39: 1-9. 2020. (IF=3.121)

Isobe, J., Maeda, S., Obata, Y., Iizuka, K., Nakamura, Y., Fujimura, Y., Kimizuka, T., Hattori, K., Kim, Y.G., Morita, T., Kimura, I., Offermanns, S., Adachi, T., Nakao, A., Kiyono, H., Takahashi, D., and *Hase, K., Commensal-bacteria-derived butyrate promotes the T-cell-independent IgA response in the colon. Int Immunol, 32: 243-58. 2020. (IF=3.519)

Aihara, Y., Fukuda, Y., Takizawa, A., Osakabe, N., Aida, T., Tanaka, K., Yoshikawa, S., Karasuyama, H., and *Adachi, T., Visualization of mechanical stress-mediated Ca(2+) signaling in the gut using intravital imaging. Biosci Microbiota Food Health, 39: 209-18. 2020. (IF=3.121)

*Yoshikawa, S., Oh-Hora, M., Hashimoto, R., Nagao, T., Peters, L., Egawa, M., Ohta, T., Miyake, K., Adachi, T., Kawano, Y., Yamanishi, Y., and Karasuyama, H., Pivotal role of STIM2, but not STIM1, in IL-4 production by IL-3-stimulated murine basophils. Sci Signal, 12. 2019. (IF=6.467)

Fujii, Y., Suzuki, K., Adachi, T., Taira, S., and *Osakabe, N., Corticotropin-releasing hormone is significantly upregulated in the mouse paraventricular nucleus following a single oral dose of cinnamtannin A2 as an (-)-epicatechin tetramer. J Clin Biochem Nutr, 65: 29-33. 2019. (IF=2.405)

*Adachi, T., Yoshikawa, S., Tezuka, H., Tsuji, N.M., Ohteki, T., Karasuyama, H., and Kumazawa, T., Propolis induces Ca(2+) signaling in immune cells. Biosci Microbiota Food Health, 38: 141-9. 2019. (IF=3.121)

Watabe, T., Nagaishi, T., Tsugawa, N., Kojima, Y., Jose, N., Hosoya, A., Onizawa, M., Nemoto, Y., Oshima, S., Nakamura, T., Karasuyama, H., Adachi, T., and *Watanabe, M., B cell activation in the cecal patches during the development of an experimental colitis model. Biochem Biophys Res Commun, 496: 367-73. 2018. (IF=2.705)

Tabakawa, Y., Ohta, T., Yoshikawa, S., Robinson, E.J., Yamaji, K., Ishiwata, K., Kawano, Y., Miyake, K., Yamanishi, Y., Ohtsu, H., Adachi, T., Watanabe, N., Kanuka, H., and *Karasuyama, H., Histamine Released From Skin-Infiltrating Basophils but not mast cells is crucial for acquired tick resistance in mice. Front Immunol, 9: 1540. 2018. (IF=4.716)

Nakagawa, Y., Ishimura, K., Oya, S., Kamino, M., Fujii, Y., Nanba, F., Toda, T., Ishii, T., Adachi, T., Suhara, Y., and *Osakabe, N., Comparison of the sympathetic stimulatory abilities of B-type procyanidins based on induction of uncoupling protein-1 in brown adipose tissue (BAT) and increased plasma catecholamine (CA) in mice. PLoS One, 13: e0201203. 2018. (IF=2.776)

*Lino, A.C., *Dang, V.D., *Lampropoulou, V., *Welle, A., Joedicke, J., Pohar, J., Simon, Q., Thalmensi, J., Baures, A., Fluhler, V., Sakwa, I., Stervbo, U., Ries, S., Jouneau, L., Boudinot, P., Tsubata, T., Adachi, T., Hutloff, A., Dorner, T., Zimber-Strobl, U., de Vos, A.F., Dahlke, K., Loh, G., Korniotis, S., Goosmann, C., Weill, J.C., Reynaud, C.A., Kaufmann, S.H.E., Walter, J., and *Fillatreau, S., LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells. Immunity, 49: 120-33 e9. 2018. (IF=21.522)

Kumazawa, T., Nishimura, A., Asai, N., and *Adachi, T., Isolation of immune-regulatory Tetragenococcus halophilus from miso. PLoS One, 13: e0208821. 2018. (IF=2.776)

Jin, K., Imada, T., Nakamura, S., Izuta, Y., Oonishi, E., Shibuya, M., Sakaguchi, H., Adachi, T., and *Tsubota, K., Intravital Two-photon Imaging of Ca(2+) signaling in Secretory Organs of Yellow Cameleon Transgenic Mice. Sci Rep, 8: 15880. 2018. (IF=4.011)

Fujii, Y., Suzuki, K., Hasegawa, Y., Nanba, F., Toda, T., Adachi, T., Taira, S., and *Osakabe, N., Single oral administration of flavan 3-ols induces stress responses monitored with stress hormone elevations in the plasma and paraventricular nucleus. Neurosci Lett, 682: 106-11. 2018. (IF=2.173)

Yoshikawa, S., Usami, T., Kikuta, J., Ishii, M., Sasano, T., Sugiyama, K., Furukawa, T., Nakasho, E., Takayanagi, H., Tedder, T.F., Karasuyama, H., Miyawaki, A., and *Adachi, T., Intravital imaging of Ca(2+) signals in lymphocytes of Ca(2+) biosensor transgenic mice: indication of autoimmune diseases before the pathological onset. Sci Rep, 6: 18738. 2016. (IF=4.259)

Akatsu, C., Shinagawa, K., Numoto, N., Liu, Z., Ucar, A.K., Aslam, M., Phoon, S., Adachi, T., Furukawa, K., Ito, N., and *Tsubata, T., CD72 negatively regulates B lymphocyte responses to the lupus-related endogenous toll-like receptor 7 ligand Sm/RNP. J Exp Med, 213: 2691-706. 2016. (IF=11.991)

*Adachi, T., Kakuta, S., Aihara, Y., Kamiya, T., Watanabe, Y., Osakabe, N., Hazato, N., Miyawaki, A., Yoshikawa, S., Usami, T., Karasuyama, H., Kimoto-Nira, H., *Hirayama, K., and *Tsuji, N.M., Visualization of Probiotic-Mediated Ca(2+) Signaling in Intestinal Epithelial Cells In Vivo. Front Immunol, 7: 601. 2016. (IF=6.429)

2016年以降（その他）

IgAと回腸炎

安達貴弘

臨床・アレルギー科（科学評論社）　Vol.78 No.2 2022年8月25日

免疫グロブリンAの欠損により回腸特異的な炎症が自然発症する

安達貴弘、永石宇司

消化器病学サイエンス　Vol.5 no.4 42－44. 2021年 2021.12.1.

【食物摂取に伴う脳腸相関の可視化技術】食シグナルを起点とした脳腸相関の可視化

安達貴弘

アグリバイオ2021年6月号　2021.06.03

安達貴弘

機能性食品と薬理栄養 14(4) 230 - 236 2021年2月

【食と健康を結ぶメディカルサイエンス生体防御系を亢進し、健康の維持に働く分子機構】(第4章)食と健康研究のための最先端技術生体イメージングによる食シグナルおよび未病・病態の解析

安達貴弘

実験医学 38(10) 1779 - 1786 2020年6月

生体イメージングによる食シグナルおよび超早期未病の可視化解析生体内のCa2+シグナルを見る

安達貴弘

化学と生物 56(5) 345 - 352 2018年4月

B細胞内のカルシウム伝達機構第5回 B細胞カルシウムシグナル.

安達貴弘(担当:共著)

炎症と免疫. 24(1)67-73 2016年1月

​

Takeuchi, Y., Fukunaga, M., Iwatani, S., Miyanaga, K., Adachi, T., Yamamoto, N. Release of an anti-anxiety peptide in casein hydrolysate with Aspergillus oryzae protease. Food Funct. 2022 Oct 17;13(20):10449-10460. doi: 10.1039/d2fo01793h.

(IF=5.396)